Epigenetics works by addition or removal of chemical tags to genes to mark which ones
should be used in different types of cells. One of the better studied tags,
known to play an important role in development and cancer, is the methyl
chemical group. Here, in a big group of same and fraternal twin pairs,
Waterland and his colleagues studied a set of genes known as metastable
epialleles. Previous work indicated that methyl tags are randomly brought to
metastable epialleles in the course of early embryonic improvement and
maintained at some stage in life.
Identical twins are formed while the very early embryo -- basically a ball of cells -- splits into parts, and every single individual continues to develop into a separate person. The authors proposed and tested a simple model to explain epigenetic supersimilarity.
Epigenetic Identical seems to arise in a small group of
genes, as the researchers determined, some of them are associated with cancer.
To test whether or not these epigenetic markers might have an effect on chance
of most cancers, the scientists in Houston teamed up with cancer
epidemiologists strolling the Cancer Council Victoria's Melbourne Collaborative
Cohort Study in Melbourne, Australia. Back in the Nineties, this huge have a
look at was installation to evaluate one of a kind chance factors for most
cancers.
"By analyzing peripheral blood DNA samples from adults
in our study, we have been in a position to expose that methylation at
epigenetically supersimilar genes is related to some types of cancers, along
with lung, prostate and colorectal cancers," said Dr. Roger Milne, associate
professor and head of Cancer Epidemiology at Cancer Council Victoria, and an
author on the study.
To know More : Website
No comments:
Post a Comment